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KMID : 0939920100420030180
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대한암학회지
2010 Volume.42 No. 3 p.180 ~ p.184
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Novel Sunitinib Strategy in Metastatic Renal Cell Carcinoma on Hemodialysis: Intermittent Dose of Sunitinib after Hemodialysis
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Yoon Sang-Hyun
Kim Ki-Hyang
Choi Jun-jeong
Kim Gun-Min
Kim Joo-Hoon
Kim Hyo-Song
Park Young-Nyun
Rha Sun-Young
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Abstract
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The proper dose and schedule of sunitinib have yet to be established for patients with metastatic renal cell carcinoma (RCC) on hemodialysis. We reviewed two patients with metastatic RCC on hemodialysis who had been treated with sunitinib in Yonsei Cancer Center, Yonsei University College of Medicine. Fifty milligrams of sunitinib was administered intermittently after each hemodialysis session (3 or 4 times a week). Overall responses were partial response in both cases. Progression-free survivals were 16 and 6 months, respectively, at the time of reporting (April 2010). Both subjects tolerated the treatment.
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KEYWORD
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Renal cell carcinoma, Sunitinib, Renal dialysis
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